Neural Determinants of Pulsatile Luteinizing Hormone Secretion in Male Mice
نویسندگان
چکیده
منابع مشابه
Pulsatile Luteinizing Hormone Secretion in Patients
The physiological and pathophysiological role of cortisol in pulsatile LH release was investigated in 14 patients (5 men, 6 premenopausal women, and 3 postmenopausal women) with Addison’s disease. The explicit effect of cortisol in relation to the effect of corticotropin-releasing factor (CRF), ACTH, and opioids was ensured by hypo-, normo-, and hypercortisolism. Hypocortisolism was obtained by...
متن کاملPulsatile luteinizing hormone secretion in the castrate male bovine: effects of testosterone or estradiol replacement therapy.
Luteinizing hormone (LH) secretory profiles have been determined for the male bovine following castration and steroid replacement therapy. Serum LH concentrations increased approximately threefold during the first week following castration and thereafter remained elevated (6.6 +/- .7 ng/ml). Castrates not receiving steroid replacement showed a rhythmic pattern of LH release that was of high fre...
متن کاملAnalysis of pulsatile and surge-like luteinizing hormone secretion with frequent blood sampling in female mice.
Mice have become more important as genetically-modified model animals for analysis of physiological functions. The establishment of a frequent blood sampling system in conscious mice would provide a powerful tool for a better and more detailed understanding of the physiological status of circulating hormonal changes, such as pulse or surge modes of luteinizing hormone (LH) secretion. Frequent b...
متن کاملHypothalamic KiSS1/GPR54 Gene Expressions and Luteinizing Hormone Plasma Secretion in Morphine Treated Male Rats
Objective The inhibitory effects of Morphine and the stimulatory influence of kisspeptin signaling have been demonstrated on GnRH/LH release. Hypothalamic kisspeptin is involved in relaying the environmental and metabolic information to reproductive axis. In the present study the role of kisspeptin/GPR54 signaling system was investigated on relaying the inhibitory effects of morphine on LH horm...
متن کاملDoes cortisol mediate endotoxin-induced inhibition of pulsatile luteinizing hormone and gonadotropin-releasing hormone secretion?
Bacterial endotoxin (lipopolysaccharide), a commonly used model of immune/inflammatory stress, inhibits reproductive neuroendocrine activity and concurrently induces a profound stimulation of the hypothalamo-pituitary-adrenal axis. We employed two approaches to test the hypothesis that enhanced secretion of cortisol mediates endotoxin-induced suppression of pulsatile GnRH and LH secretion in th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Endocrinology
سال: 2020
ISSN: 0013-7227,1945-7170
DOI: 10.1210/endocr/bqz045